Key objectives of the EUPLAN initiative
- Translation of platelet genomics and proteomics knowledge into platelet function research in relation to thrombosis and bleeding.
- Identification and test of novel anti-platelet agents with high potential to prevent arterial thrombosis without side effect of bleeding.
- Establishment of the regulation of megakaryocytopoiesis and platelet production
- Characterization of new platelet mutations or genes throughout Europe that contribute to hemostasis and may lead to congenital bleeding disorders.
- Validation of system biology approaches to investigate platelet function.
- Development of new tests for the assessment of platelet function and for monitoring parameters of platelet functionality in the course of anti-thrombotic therapies.
- Integrated research to initiate clinical studies to test new anti-platelet medication.