Key objectives of the EUPLAN initiative

  • Translation of platelet genomics and proteomics knowledge into platelet function research in relation to thrombosis and bleeding.
  • Identification and test of novel anti-platelet agents with high potential to prevent arterial thrombosis without side effect of bleeding.
  • Establishment of the regulation of megakaryocytopoiesis and platelet production
  • Characterization of new platelet mutations or genes throughout Europe that contribute to hemostasis and may lead to congenital bleeding disorders.
  • Validation of system biology approaches to investigate platelet function.
  • Development of new tests for the assessment of platelet function and for monitoring parameters of platelet functionality in the course of anti-thrombotic therapies.
  • Integrated research to initiate clinical studies to test new anti-platelet medication.